Urinary albumin and retinol-binding protein in diabetes.

Urinary albumin and retinol-binding protein in diabetes.

Above-normal urinary excretion of albumin and retinol-binding protein in patients with acute myocardial infarction.

Concentrations of albumin and retinol-bindung protein (REP) in urine are more sensitive indicators of renal dysfunction in hypertensive patients than the serum creatinmne concentration and the Albustix#{174}reaction (Ames, Tarrytown, NY) (1). Many patients with heart failure had abovenormal urinary albumin and REP concentrations (2), and these values decreased as the patients were treated with ...

Urinary Tamm‐Horsfall protein, albumin, vitamin D‐binding protein, and retinol‐binding protein as early biomarkers of chronic kidney disease in dogs

Proteinuria is a marker and mediator of chronic kidney disease (CKD). In clinical practice, the urinary protein-to-creatinine ratio (UP/C) is of limited usefulness, because it indicates only the magnitude of proteinuria and not the origin of the loss (glomerular or tubular). The complete assessment of proteinuria includes quantitative and qualitative evaluations, both of which are required in o...

Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis

Activated hepatic stellate cells (HSCs) play a key role in liver fibrosis, and inactivating HSCs has been considered a promising therapeutic approach. We previously showed that albumin and its derivative designed for stellate cell-targeting, retinol-binding protein-albumin domain III fusion protein (referred to as R-III), inactivate cultured HSCs. Here, we investigated the mechanism of action o...

Confocal immunolocalization of bovine serum albumin, serum retinol-binding protein, and interphotoreceptor retinoid-binding protein in bovine retina.

PURPOSE Recently it has been shown that the transport as well as clearance of retinol from isolated rod photoreceptors requires an extracellular factor. Interphotoreceptor retinoid-binding protein (IRBP) is a component of the interphotoreceptor matrix (IPM) and is known to bind visual cycle retinoids. Serum albumin and serum retinol-binding protein (sRBP), proteins capable of binding retinoids,...